Dimethylformamide → HCID 19001732, compound

HRID 1038270Notes

Reaction equation

HRID 1038270 reaction equation
[CH:1]([CH:3](Cl)[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)=[CH2:2].CN(C)C=O.[N-:16]=[N+:17]=[N-:18].[Na+]>O>[CH:1]([CH:3]([N:16]=[N+:17]=[N-:18])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)=[CH2:2]

Participants

5

Reactant 3

HCID 6228DimethylformamideHCID 33557Sodium AzideHCID 11768772Benzene, 1-(chloromethyl)-3(or 4)-ethenyl-

Product 1

HCID 19001732HCID 19001732, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To a 100 ml round bottom flask equipped with a stir bar, 4.0 g (26.2 mm) of vinylbenzyl chloride, and 10 ml of dimethylformamide (DMF) were added. To this solution 3.40 g (52.4 mm) of sodium azide was added and the reaction mixture was stirred at room temperature overnight, after which time 50 ml of deionized water were added to the solution. The resulting 4-vinyl benzyl azide was extracted from the reaction solution with ethyl ether. The product was confirmed by 1H NMR.

Workup

  1. customTo a 100 ml round bottom flask equipped with a stir bar
  2. extractionThe resulting 4-vinyl benzyl azide was extracted from the reaction solution with ethyl ether

Sources & evidence

ORD record
ord-d6b864a90d584daf8208de4b7d8bcda2
Source dataset
uspto-grants-2013_10
Patent number
US08550256B1

Reaction notes

Loading…