2-Methoxyethylamine → HCID 86627058, compound

HRID 1038291Notes

Reaction equation

HRID 1038291 reaction equation
C(O[C:9]1[C:21]([C:22]([N:24]2[CH2:28][CH2:27]SC2=S)=[O:23])=[CH:20][C:12]([C:13]([NH:15][CH2:16][CH2:17][O:18][CH3:19])=[O:14])=[CH:11][C:10]=1[C:30]([N:32]1[CH2:36][CH2:35][S:34][C:33]1=[S:37])=[O:31])C1C=CC=CC=1.[CH2:38]([O:45]C1C(C(N2CCSC2=S)=O)=CC(C(N2CCSC2=S)=O)=CC=1C(N1CCSC1=S)=O)[C:39]1[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=1.[CH3:76][O:77]CCN>>[CH2:38]([O:45][C:11]1[C:10]([C:30]([N:32]2[CH2:36][CH2:35][S:34][C:33]2=[S:37])=[O:31])=[CH:9][C:21]([C:22]([NH:24][CH2:28][CH2:27][O:77][CH3:76])=[O:23])=[CH:20][C:12]=1[C:13]([NH:15][CH2:16][CH2:17][O:18][CH3:19])=[O:14])[C:39]1[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=1

Participants

4

Reactant 3

HCID 80182-MethoxyethylamineHCID 57572484HCID 57572484, compound2×HCID 57572485HCID 57572485, compound

Product 1

HCID 86627058HCID 86627058, compoundYield 73%

Procedure

This compound was prepared by the same procedure as compound 18A except the molar ratio of compound 17 and 2-methoxyethylamine was 1:2 instead of compound 17 in large excess. Separation and purification were performed as described for compound 18A. Pure material was obtained as thick, bright, yellow oil; yield: 73%.

Workup

  1. customSeparation and purification
  2. customPure material was obtained as thick, bright, yellow oil

Sources & evidence

ORD record
ord-9dcf75748d92458a94b41cb1e44f4835
Source dataset
uspto-grants-2013_10
Patent number
US08551453B2

Reaction notes

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