Ethyl isothiocyanatoformate → HCID 59437446, compound

HRID 1038356Notes

Reaction equation

HRID 1038356 reaction equation
[CH2:1]([O:3][C:4]([N:6]=[C:7]=[S:8])=[O:5])[CH3:2].[Br:9][C:10]1[CH:11]=[CH:12][C:13]([NH2:17])=[N:14][C:15]=1[CH3:16]>O1CCOCC1>[CH2:1]([O:3][C:4](=[O:5])[NH:6][C:7](=[S:8])[NH:17][C:13]1[CH:12]=[CH:11][C:10]([Br:9])=[C:15]([CH3:16])[N:14]=1)[CH3:2]

Participants

4

Reactant 2

HCID 85320Ethyl isothiocyanatoformateHCID 1706782-Pyridinamine, 5-bromo-6-methyl-

Product 1

HCID 59437446HCID 59437446, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

Ethoxycarbonylisothiocyanat (7.71 g) was added to a stirred solution of 5-bromo-6-methylpyridin-2-amine (10.0 g) in dioxane (90 ml). The mixture was stirred for 2 h at r.t. A white solid precipitated. Hexane (100 ml) was added and the white solid was collected by filtration.

Workup

  1. customA white solid precipitated
  2. additionHexane (100 ml) was added
  3. filtrationthe white solid was collected by filtration

Sources & evidence

ORD record
ord-52e46e09fa4e4de386e15e52969ef379
Source dataset
uspto-grants-2013_10
Patent number
US08551980B2

Reaction notes

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