Hydrochloric Acid → HCID 58407649, compound

HRID 1038385Notes

Reaction equation

HRID 1038385 reaction equation
[CH2:1]([S:8][C:9]1[C:17]2[C:12](=[CH:13][CH:14]=[C:15]([CH:18]3OCC[O:19]3)[CH:16]=2)[N:11](COCC[Si](C)(C)C)[N:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl>C(O)C>[CH2:1]([S:8][C:9]1[C:17]2[C:12](=[CH:13][CH:14]=[C:15]([CH:18]=[O:19])[CH:16]=2)[NH:11][N:10]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 313Hydrochloric Acid2×HCID 58407623HCID 58407623, compound

Product 1

HCID 58407649HCID 58407649, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
90 °C

Procedure

The product mixture obtained in Example 7A was dissolved in ethanol (4 ml), treated with 3 N hydrochloric acid (1 ml) and heated to 90° C. for 4 h. After this time, 3 N hydrochloric acid (0.2 ml) was again added, and heating was continued for 3 h. The mixture was evaporated to dryness, and the crude product thus obtained was used in the next step without further purification.

Workup

  1. temperatureheating
  2. customThe mixture was evaporated to dryness

Sources & evidence

ORD record
ord-e5de6acca3e8418c9383a310fc7c3eda
Source dataset
uspto-grants-2013_10
Patent number
US08551989B2

Reaction notes

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