反应详情

温度

90 °C

To a solution of 170 mg (0.583 mmol) 5-(1,3-dioxan-2-yl)-N-(2-methoxyethyl)-N-methyl-1H-indazol-3-amine (Example 47A) in ethanol (10 ml) were added 1.9 ml (5.83 mmol) 3 M hydrochloric acid, and the solution was heated to 90° C. for 30 min. After cooling, the mixture was concentrated under reduced pressure. The remaining material (135 mg, 99% of th.) was used in the next step without further purification.

1. temperatureAfter cooling
2. concentrationthe mixture was concentrated under reduced pressure
3. customThe remaining material (135 mg, 99% of th.) was used in the next step without further purification