HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl piperazine-1-carboxylate → 4-[4-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)-2-nitrophenyl]piperazine-1-carboxylic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl piperazine-1-carboxylate | HCID 143452 | — |
| Reactant | 1,1,1,3,3,3-Hexafluoro-2-(4-fluoro-3-nitrophenyl)propan-2-ol | HCID 86647210 | — |
| Product | 4-[4-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)-2-nitrophenyl]piperazine-1-carboxylic acid tert-butyl ester | HCID 86647209 | — |
Reaction Steps
1,1,1,3,3,3-Hexafluoro-2-(4-fluoro-3-nitrophenyl)propan-2-ol and tert-butyl piperazine-1-carboxylate were used for a similar reaction and treatment as Example 6-b), and the title compound was obtained as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08551985B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-699196e4b45b40c2936f6e0fd28d2127 |
| Source note | uspto-grants-2013_10 |