HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 66597864, compound → 3-[2-((S)-4-{4-[2-(benzyloxy)-1,1,1,3,3,3-hexafluoropropan-2-yl]-2-(prop-1-en-1-yl)phenyl}-3-methylpiperazin-1-yl)-2-oxoethyl]-5-[5-(1-methylethoxy)pyridin-2-yl]-5-methylimidazolidine-2,4-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 66597864 | HCID 66597864 | — |
| Reactant | 5-[5-(1-Methylethoxy)pyridin-2-yl]-5-methylimidazolidine-2,4-dione | HCID 66598054 | — |
| Reactant | HCID 86647212 | HCID 86647212 | — |
| Product | 3-[2-((S)-4-{4-[2-(benzyloxy)-1,1,1,3,3,3-hexafluoropropan-2-yl]-2-(prop-1-en-1-yl)phenyl}-3-methylpiperazin-1-yl)-2-oxoethyl]-5-[5-(1-methylethoxy)pyridin-2-yl]-5-methylimidazolidine-2,4-dione | HCID 86647214 | — |
Reaction Steps
(S)-1-(4-{4-[2-(benzyloxy)-1,1,1,3,3,3-hexafluoropropan-2-yl]-2-(prop-1-en-1-yl)phenyl}-3-methylpiperazin-1-yl)-2-bromoethanone, 5-(2,3-dihydrobenzofuran-6-yl)-5-methylimidazolidine-2,4-dione and 5-[5-(1-methylethoxy)pyridin-2-yl]-5-methylimidazolidine-2,4-dione were used for a similar reaction and treatment as Example 14-1, and the title compound was obtained as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08551985B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-39452a16b9a9471ebd0bac6e4c4601a7 |
| Source note | uspto-grants-2013_10 |