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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1038693Generated: October 31, 2026

2,4-Difluoroaniline → N4-(2,4-difluorophenyl)-N6-methylpyrimidine-4,6-diamine

https://huagongshe.com/reaction/1038693

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DifluoroanilineHCID 9709—
Reactant6-chloro-N-methylpyrimidin-4-amineHCID 309479—
ProductN4-(2,4-difluorophenyl)-N6-methylpyrimidine-4,6-diamineHCID 66669984—

Reaction Steps

The title compound is prepared analogously as described in Example 114A from (6-chloro-pyrimidin-4-yl)-methylamine and 2,4-difluoroaniline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08552002B2
Source datasetuspto-grants-2013_10
ORD IDord-94719721919f41d890733362b8096c15
Source noteuspto-grants-2013_10