反应详情

A solution of N-(3-chloro-phenyl)-pyrimidine-4,6-diamine (110 mg, 0.5 mmol) and 2-chlorophenyl isocyanate (60 μL, 0.5 mmol) in diglyme (1.5 mL) is stirred at 80° C. for 18 h. The precipitate which formed over time is filtered and washed with hexane/ethyl acetate to afford the pure title compound (98 mg, 52%).

1. customThe precipitate which formed over time
2. filtrationis filtered
3. washwashed with hexane/ethyl acetate