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HRID1038931

反应详情

EQUATION

反应方程式

HRID 1038931 的结构方程式

REACTANTS

反应物

2
结构：O=c1[nH]c2ccccc2c(=O)o1
HCID8359

2H-3,1-Benzoxazine-2,4(1H)-dione

C8H5NO3

结构：Nc1ccccn1
HCID10439

2-Aminopyridine

C5H6N2

PRODUCTS

生成物

1
结构：Nc1ccccc1C(=O)Nc1ccccn1
HCID276325

2-Amino-N-(pyridin-2-yl)benzene-1-carboximidic acid

C12H11N3O

收率 54%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1COCCO1
溶剂HCID31275

1,4-Dioxane

C4H8O2

PROCEDURE

实验过程

A mixture of isatoic anhydride 71 (8.7 g, 0.053 mol) and 2-aminopyridine (5 g, 0.06 mol) was heated in dioxane (30 mL) for 6-7 hours. After cooling, the solvent was evaporated in vacuo, the residue treated with water and recrystallized from EtOH/H2O to yield 72 (6 g, 54%).

WORKUP

后处理

  1. temperatureAfter cooling
  2. customthe solvent was evaporated in vacuo
  3. additionthe residue treated with water
  4. customrecrystallized from EtOH/H2O