HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isatoic Anhydride → 2-amino-N-(pyridin-2-yl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isatoic Anhydride | HCID 8359 | — |
| Reactant | 2-Aminopyridine | HCID 10439 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 2-amino-N-(pyridin-2-yl)benzamide | HCID 276325 | 54% |
Reaction Steps
A mixture of isatoic anhydride 71 (8.7 g, 0.053 mol) and 2-aminopyridine (5 g, 0.06 mol) was heated in dioxane (30 mL) for 6-7 hours. After cooling, the solvent was evaporated in vacuo, the residue treated with water and recrystallized from EtOH/H2O to yield 72 (6 g, 54%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08552009B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-a4ba31314b7b40a2a3232c4beaa6d4cc |
| Source note | uspto-grants-2013_10 |