反应详情

A mixture of 72 (3 g, 0.015 mol) and 1,1,1-triethoxy-ethane (5 g, 0.045 mol) were heated for 7 hours. The reaction mixture was poured into water, filtered, and the precipitate was washed with water and recrystallized from EtOH to yield 73 (2.5 g, 75%). M. Wt. 237. LCMS [M+H]+=238.

1. temperaturewere heated for 7 hours
2. filtrationfiltered
3. washthe precipitate was washed with water
4. customrecrystallized from EtOH