HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromo-1-methyl-1,2-dihydropyridin-2-one → 8-(1-Methyl-2-oxo-1,2-dihydropyridin-3-yl)-2-(4-(trifluoromethoxy)phenyl)-2,8-diazaspiro[4.5]decan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromo-1-methyl-1,2-dihydropyridin-2-one | HCID 13024025 | — |
| Reactant | 2-(4-(Trifluoromethoxy)phenyl)-2,8-diazaspiro[4.5]decan-1-one | HCID 66742759 | — |
| Product | 8-(1-Methyl-2-oxo-1,2-dihydropyridin-3-yl)-2-(4-(trifluoromethoxy)phenyl)-2,8-diazaspiro[4.5]decan-1-one | HCID 66742707 | — |
Reaction Steps
The title compound was prepared in analogy to example 1 step D from a mixture of 2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one (described in example 1 step C) and 3-bromo-1-methyl-1H-pyridin-2-one. Light yellow solid. MS (ESI): 422.1 (MH+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08552024B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-96ef13da4c8c4854af1154b5a1a40e4c |
| Source note | uspto-grants-2013_10 |