3-Bromo-1-methyl-1,2-dihydropyridin-2-one → HCID 56655537, compound

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Reaction Steps

The title compound was prepared in analogy to example 1 step D from a mixture of 2-[4-((S)-2,2,2-trifluoro-1-methylethoxy)-phenyl]-2,8-diaza-spiro[4.5]decan-1-one (prepared in analogy to example 1 step B-C from 1-benzyl-4-(2-methoxyethyl)-piperidine-4-carboxylic acid ethyl ester and 4-((S)-2,2,2-trifluoro-1-methyl-ethoxy)-phenylamine) and 3-bromo-1-methyl-1H-pyridin-2-one. Light green solid. MS (ESI): 450.1 (MH+)

Provenance & Evidence