HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-nitro-2-(1H-1,2,4-triazol-1-yl)pyridine → 6-(1H-1,2,4-Triazol-1-yl)pyridin-3-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-nitro-2-(1H-1,2,4-triazol-1-yl)pyridine | HCID 2766764 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 6-(1H-1,2,4-Triazol-1-yl)pyridin-3-amine | HCID 16772327 | — |
Reaction Steps
5-nitro-2-(1H-1,2,4-triazol-1-yl)pyridine (100 mg, 0.523 mmol) from step 1 of this example was added Pd/C (111 mg, 0.105 mmol) and methanol (5.2 mL). Set the reaction on Parr Shaker at 50 psi (345 kPa) for overnight. The solution was filtered through CELITE and rinsed with methanol to give the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08552022B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-fbe714709af342a7b7b3c79361752d35 |
| Source note | uspto-grants-2013_10 |