関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Ethyl Acetate | HCID 8857 | — |
| 反応物 | Piperidin-4-ol | HCID 79341 | — |
| 反応物 | O-methyl hydrazinecarbothioate | HCID 10171237 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | HCID 55281286 | HCID 55281286 | — |
反応手順
A solution of methyl hydrazinecarbothioate (1.0 g, 8.2 mmol) and piperidin-4-ol (1.24 g, 12.3 mmol) in ethanol (7 mL) was refluxed with heating at 90° C. for 2 days. After addition of ethyl acetate, the reaction solution was washed with saturated aqueous sodium chloride, dried over anhydrous magnesium sulfate and concentrated to give the crude desired product. The crude product was used directly for the next reaction.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08552031B2 |
|---|
| 出典データセット | uspto-grants-2013_10 |
|---|
| ORD ID | ord-ffdf41338bfb4baf90c4987ed35a4d2c |
|---|
| 出典メモ | uspto-grants-2013_10 |
|---|
