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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1039641Generated: November 1, 2026

5-Hydroxypyridine-2-carboxylic acid → N-((R)-5-Bromoindan-2-yl)-5-hydroxypyridine-2-carboxamide

https://huagongshe.com/reaction/1039641

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Hydroxypyridine-2-carboxylic acidHCID 268740—
Reactant1H-Inden-2-amine, 5-bromo-2,3-dihydro-, (2R)-HCID 11275870—
ProductN-((R)-5-Bromoindan-2-yl)-5-hydroxypyridine-2-carboxamideHCID 66679915—

Reaction Steps

According to method C, 5-hydroxypyridine-2-carboxylic acid was reacted with (R)-5-bromo-indan-2-ylamine. This afforded the product with the molecular weight of 333.19 (C15H13BrN2O2); MS (ESI); 333 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08552199B2
Source datasetuspto-grants-2013_10
ORD IDord-c518c434b15f46268b2410ee9a9d0637
Source noteuspto-grants-2013_10