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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 104015Generated: October 29, 2026

Tetrahydrofuran → 6-Methyl-1-(2,2,2-trifluoroethyl)-5-(2,3,5-trifluorophenyl)pyridin-2(1H)-one

https://huagongshe.com/reaction/104015

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantFluoride IonHCID 28179—
ReactantCesium cationHCID 104967—
Reactant2,3,5-Trifluorophenylboronic AcidHCID 4078843—
Reactant5-Bromo-6-methyl-1-(2,2,2-trifluoroethyl)pyridin-2(1H)-oneHCID 68751151—
Product6-Methyl-1-(2,2,2-trifluoroethyl)-5-(2,3,5-trifluorophenyl)pyridin-2(1H)-oneHCID 86665208—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-1c4b76ea1e324e2cbd636c7e5e8ecea4
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)