Tetrahydrofuran → 6-Methyl-1-(2,2,2-trifluoroethyl)-5-(2,3,5-trifluorophenyl)pyridin-2(1H)-one
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5](=[O:14])[n:6]([CH2:9][C:10]([F:11])([F:12])[F:13])[c:7]1[CH3:8].[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[Cs+:28].[F-:27].[F:15][c:16]1[c:17]([B:24]([OH:25])[OH:26])[cH:18][c:19]([F:23])[cH:20][c:21]1[F:22]>>[c:2]1(-[c:17]2[c:16]([F:15])[c:21]([F:22])[cH:20][c:19]([F:23])[cH:18]2)[cH:3][cH:4][c:5](=[O:14])[n:6]([CH2:9][C:10]([F:11])([F:12])[F:13])[c:7]1[CH3:8]Participants
6
Sources & evidence
- ORD record
- ord-1c4b76ea1e324e2cbd636c7e5e8ecea4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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