Benzyl Bromide → HCID 66721136, compound

HRID 1040360Notes

Reaction equation

HRID 1040360 reaction equation
[I:1][C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][C:3]=1[OH:11].[CH2:12](Br)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[CH2:12]([O:11][C:3]1[CH:4]=[C:5]([N+:8]([O-:10])=[O:9])[CH:6]=[CH:7][C:2]=1[I:1])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 7498Benzyl BromideHCID 186726022-Iodo-5-nitrophenol

Product 1

HCID 66721136HCID 66721136, compoundYield 90.4%

Procedure

According to the method described in example 4.1., starting from 20.8 g (78.5 mmol) of 2-iodo-5-nitrophenol and 9.3 mL (78.5 mmol) of benzyl bromide, we obtain 25.2 g of 2-(benzyloxy)-1-iodo-4-nitrobenzene in the form of oil.

Sources & evidence

ORD record
ord-a20bb67633504a678aed26194d0a2a6d
Source dataset
uspto-grants-2013_10
Patent number
US08552201B2

Reaction notes

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