Hydrochloric Acid → HCID 178516168, compound

Participants

Reaction Steps

To a solution of (R)-3-(5-hydroxy-1H-pyrazol-3-yl)-pyrrolidine-1-carboxylic acid tert-butyl ester (44 mg, 0.17 mmol) in CH2Cl2 (1 mL) was added HCl in dioxane (0.2 mL, 4.0 M). The reaction mixture was stirred for 48 h. Solvent was removed at reduced pressure to afford crude (R)-5-pyrrolidin-3-yl-2H-pyrazol-3-ol as a white solid. The material was used without further purification.

Provenance & Evidence