1-(3-Ethyl-1,2,4-oxadiazol-5-yl)cyclopropan-1-amine hydrochloride → 1-[5-(1-Amino-cyclopropyl)-1,2,4-oxadiazol-3-yl]-propan-2-ol hydrochloride

Participants

Role	Name	HCID	Charge
Reactant	1-(3-Ethyl-1,2,4-oxadiazol-5-yl)cyclopropan-1-amine hydrochloride	HCID 67389635	—
Reactant	2-[5-(1-Amino-cyclopropyl)-1,2,4-oxadiazol-3-yl]-ethanol hydrochloride	HCID 67389754	—
Reactant	1-[3-(2,2,2-Trifluoro-ethyl)-1,2,4-oxadiazol-5-yl]-cyclopropylamine hydrochloride	HCID 67389916	—
Reactant	1-(3-Isopropyl-1,2,4-oxadiazol-5-yl)-cyclopropylamine hydrochloride	HCID 67390319	—
Reactant	1-(5-Methyl-1,2,4-oxadiazol-3-yl)cyclopropan-1-amine hydrochloride	HCID 67390432	—
Reactant	1-(5-Cyclopropyl-1,2,4-oxadiazol-3-yl)cyclopropan-1-amine hydrochloride	HCID 67390539	—
Reactant	[5-(1-Amino-cyclopropyl)-1,2,4-oxadiazol-3-yl]-dimethyl-amine hydrochloride	HCID 67391075	—
Reactant	1-(5-Isopropyl-1,2,4-oxadiazol-3-yl)-cyclopropylamine hydrochloride	HCID 67391079	—
Product	1-[5-(1-Amino-cyclopropyl)-1,2,4-oxadiazol-3-yl]-propan-2-ol hydrochloride	HCID 67390211	—

Reaction Steps

The following compounds were prepared using similar procedures as described above: [5-(1-Amino-cyclopropyl)-1,2,4-oxadiazol-3-yl]-dimethyl-amine hydrochloride, 2-[5-(1-Amino-cyclopropyl)-1,2,4-oxadiazol-3-yl]-ethanol hydrochloride, 1-[3-(2,2,2-Trifluoro-ethyl)-1,2,4-oxadiazol-5-yl]-cyclopropylamine hydrochloride, 1-(3-Ethyl-1,2,4-oxadiazol-5-yl)-cyclopropylamine hydrochloride, 1-(3-Isopropyl-1,2,4-oxadiazol-5-yl)-cyclopropylamine hydrochloride, 1-(5-Methyl-1,2,4-oxadiazol-3-yl)-cyclopropylamine hydrochloride, 1-(5-Isopropyl-1,2,4-oxadiazol-3-yl)-cyclopropylamine hydrochloride, 1-(5-Cyclopropyl-1,2,4-oxadiazol-3-yl)-cyclopropylamine hydrochloride.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08552205B2
Source dataset	uspto-grants-2013_10
ORD ID	ord-cae9f8e6ae6749be9362f885c2b62400
Source note	uspto-grants-2013_10