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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1040446Generated: October 31, 2026

Hydrochloric Acid → HCID 86657590, compound

https://huagongshe.com/reaction/1040446

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant1-Oxazolo[4,5-b]pyridin-2-ylcyclopropanamineHCID 58431160—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 86657590HCID 8665759069%

Reaction Steps

The Boc-protected 1-(1-oxazolo[4,5-b]pyridin-2-yl-cyclopropylamine (0.044 g, 0.160 mmol) was dissolved in 1,4-dioxane (0.5 mL) and to this solution was added 4N HCl in dioxane (2.50 mL, 10.9 mmol). The solution was stirred for 2 h. A ppt formed and the volatiles were removed in vacuo to afford 1-(1-oxazolo[4,5-b]pyridin-2-yl-cyclopropylamine dihydrochloride as a tan solid (0.023 g, 69%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08552205B2
Source datasetuspto-grants-2013_10
ORD IDord-13382f0f4d104fc0af798953b8b1f5c6
Source noteuspto-grants-2013_10