HCID 86657591, compound → HCID 58431095, compound

HRID 1040451Notes

Reaction equation

HRID 1040451 reaction equation
OC(C(F)(F)F)=O.[CH:8]([N:11]1[CH:15]=[C:14]([C:16]#[N:17])[N:13]=[CH:12]1)([CH3:10])[CH3:9]>CCOC(C)=O>[CH:8]([N:11]1[CH:15]=[C:14]([C:16]#[N:17])[N:13]=[CH:12]1)([CH3:10])[CH3:9]

Participants

3

Reactant 1

HCID 86657591HCID 86657591, compound

Product 1

HCID 58431095HCID 58431095, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

1-Isopropyl-1H-imidazole-4-carbonitrile TFA salt was dissolved in EtOAc, washed with sat. NaHCO3, brine, dried under anhy. Na2SO4, filtered and concentrated to afford 200 mg of 1-isopropyl-1H-imidazole-4-carbonitrile as a colorless oil, m/z 136.5 [M+1]+.

Workup

  1. washwashed with sat. NaHCO3, brine
  2. customdried under anhy
  3. filtrationNa2SO4, filtered
  4. concentrationconcentrated

Sources & evidence

ORD record
ord-03b21741efe944629cf154d6515ca7dc
Source dataset
uspto-grants-2013_10
Patent number
US08552205B2

Reaction notes

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