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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1040502Generated: October 26, 2026

Homoserine lactone hydrobromide → 2-Amino-4-bromobutanoic acid hydrobromide

https://huagongshe.com/reaction/1040502

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHomoserine lactone hydrobromideHCID 73508—
SolventAcetic AcidHCID 176—
SolventHydrogen BromideHCID 260—
Product2-Amino-4-bromobutanoic acid hydrobromideHCID 1387799264%

Reaction Conditions

Temperature100 °C

Reaction Steps

A suspension of α-amino-γ-butyrolactone hydrobromide in 30% HBr in HOAc was heated at 100° C. in a sealed tube for 5 days. The mixture was concentrated to give a white solid that was washed with Et2O to provide 23.1 g (64%) of 2-amino-4-bromo-butyric acid hydrobromide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08552205B2
Source datasetuspto-grants-2013_10
ORD IDord-f38f179cf9dd4131a13e1590a509ceb1
Source noteuspto-grants-2013_10