3-Ethyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylamine → HCID 131730897, compound

Participants

Reaction Steps

Example 219 was synthesized analogously to Example 216 replacing 3-Ethyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylamine with 7,7-Difluoro-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-ylamine 5-Chloro-N*2*-(7,7-difluoro-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-N*4*-[2-(1-methyl-1H-imidazol-2-yl)-phenyl]-pyrimidine-2,4-diamine was isolated as a foam. LC/MS (ESI)=481.96 (M+H). 1H NMR (400 MHz, DMSO, d6) δ 9.09 (m, 2H), 8.12 (s, 1H), 7.74 (m, 5H), 7.56 (m, 1H), 7.41 (s, 1H), 7.26 (m, 1H), 6.99 (d, 1H, J=8.09 Hz), 3.61 (s, 3H), 2.67 (m, 2H), 2.50 (m, 2H), 1.96 (m, 4H).

Provenance & Evidence