Dichloromethane → N-(6-chloro-5-ethylpyridin-2-yl)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamide

HRID 104107Notes

Reaction equation

HRID 104107 reaction equation
[CH3:18][CH2:19][N:20]([CH2:21][CH3:22])[CH2:23][CH3:24].[Cl:25][c:26]1[c:27]([CH2:33][CH3:34])[cH:28][cH:29][c:30]([NH2:32])[n:31]1.[Cl:35][CH2:36][Cl:37].[F:1][C:2]1([F:17])[O:3][c:4]2[c:5]([cH:7][cH:8][c:9]([C:11]3([C:14](=[O:15])[Cl:16])[CH2:12][CH2:13]3)[cH:10]2)[O:6]1>>[F:1][C:2]1([F:17])[O:3][c:4]2[c:5]([cH:7][cH:8][c:9]([C:11]3([C:14](=[O:15])[NH:32][c:30]4[cH:29][cH:28][c:27]([CH2:33][CH3:34])[c:26]([Cl:25])[n:31]4)[CH2:12][CH2:13]3)[cH:10]2)[O:6]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 575168501-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropanecarbonyl chlorideHCID 591659851004294-54-5

Product 1

HCID 59165835N-(6-chloro-5-ethylpyridin-2-yl)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamide

Sources & evidence

ORD record
ord-2594573dee194bb08beb1200c368dbd4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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