Ethanol → Ethyl 2-(4-pyrimidin-2-ylpiperazin-1-yl)hexanoate

HRID 104133Notes

Reaction equation

HRID 104133 reaction equation
[Br:13][CH:14]([C:15](=[O:16])[O:17][CH2:18][CH3:19])[CH2:20][CH2:21][CH2:22][CH3:23].[CH3:30][CH2:31][OH:32].[CH3:34][CH2:35][O:36][C:37]([CH3:38])=[O:39].[K+:24].[K+:25].[O-:26][C:27]([O-:28])=[O:29].[OH2:33].[n:1]1[c:2]([N:7]2[CH2:8][CH2:9][NH:10][CH2:11][CH2:12]2)[n:3][cH:4][cH:5][cH:6]1>>[n:1]1[c:2]([N:7]2[CH2:8][CH2:9][N:10]([CH:14]([C:15](=[O:16])[O:17][CH2:18][CH3:19])[CH2:20][CH2:21][CH2:22][CH3:23])[CH2:11][CH2:12]2)[n:3][cH:4][cH:5][cH:6]1

Participants

8

Reactant 7

HCID 702EthanolHCID 813Potassium Cation2×HCID 962WaterHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 79072Ethyl 2-bromohexanoateHCID 887471-(2-Pyrimidinyl)piperazine

Product 1

HCID 19810538Ethyl 2-(4-pyrimidin-2-ylpiperazin-1-yl)hexanoate

Sources & evidence

ORD record
ord-01ff6c9c94564bb78806cf2c8287f720
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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