HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Benzyloxy)-N,N-diethylacetamide → N,N-Diethyl-2-hydroxyacetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Benzyloxy)-N,N-diethylacetamide | HCID 60645850 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | N,N-Diethyl-2-hydroxyacetamide | HCID 4137580 | — |
Reaction Steps
2.20 g (9.9 mmol) of 2-(benzyloxy)-N,N-diethylacetamide were dissolved in 45 ml of ethyl acetate, and 200 mg of Pd/C (10%) were added. The reaction mixture was stirred under an atmosphere of hydrogen for 24 hours and then filtered through kieselguhr. The filtrate was evaporated to dryness, and N,N-diethyl-2-hydroxyacetamide was obtained as a colorless residue.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08557741B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-c4389c5a181347da859a63925e12a99d |
| Source note | uspto-grants-2013_10 |