Trifluoroacetic acid → HCID 86624963, compound

Participants

Reaction Steps

A solution of 2.50 g (6.92 mmol) 4b, 60 ml dest. water and 60 ml trifluoroacetic acid was refluxed for 2 days. The reaction mixture was evaporated, dried by use of oil pump vacuum over night and treated with diethyl ether. The resulting solid was filtered, washed extensively with diethyl ether and dried by oil pump vacuum. The solid crude product 4c was obtained in 100% yield (2.40 g; 6.92 mmol) and crude compound 4c was used for the next step without purification.

Provenance & Evidence