1,3-Propanediol → HCID 178520875, compound

Participants

Reaction Conditions

Reaction Steps

A 2 mL microwave vial was charged with a magnetic stirring bar, 4-chloro-2-morpholino-8-phenylchromenylium chloride (78) (50 mg, 138 μmol), 1,3-propanediol (1 mL), and N,N-diisopropylethylamine (48 μL, 276 μmol). The vial was sealed, and the reaction mixture was magnetically stirred and heated under microwave irradiation to 120° C. for 10 minutes in a microwave reactor to give 4-(3-hydroxypropoxy)-2-morpholino-8-phenylchromenylium chloride (79).

Provenance & Evidence