Ethanol → HCID 178466887, compound

HRID 1042044Notes

Reaction equation

HRID 1042044 reaction equation
[Cl-].[Cl:2][C:3]1[C:12]2[C:7](=[C:8]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[CH:9]=[CH:10][CH:11]=2)[O+:6]=[C:5]([N:19]2[CH2:24][CH2:23][O:22][CH2:21][CH2:20]2)[CH:4]=1.[O-:25][CH2:26][CH3:27].[Na+].C(O)C>C(Cl)(Cl)Cl>[Cl-:2].[CH2:26]([O:25][C:3]1[C:12]2[C:7](=[C:8]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[CH:9]=[CH:10][CH:11]=2)[O+:6]=[C:5]([N:19]2[CH2:24][CH2:23][O:22][CH2:21][CH2:20]2)[CH:4]=1)[CH3:27]

Participants

5

Reactant 3

HCID 702EthanolHCID 2723922Sodium ethoxideHCID 178478242HCID 178478242, compound

Product 1

HCID 178466887HCID 178466887, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

A vial was charged with a magnetic stirring bar, 4-chloro-2-morpholino-8-phenylchromenylium chloride (78) (50 mg, 138 μmol), chloroform (1.0 mL), and a solution of sodium ethoxide in ethanol (21%, 108 μL, 290 μmol). The mixture was magnetically stirred at room temperature for 1 hour to give 4-ethoxy-2-morpholino-8-phenylchromenylium chloride (80).

Workup

  1. additionA vial was charged with a magnetic stirring bar

Sources & evidence

ORD record
ord-cc7c961a4e8a4275b8a315f761f2d0c3
Source dataset
uspto-grants-2013_10
Patent number
US08557807B2

Reaction notes

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