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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1042128Generated: November 2, 2026

HCID 59072103, compound → HCID 66726181, compound

https://huagongshe.com/reaction/1042128

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 59072103HCID 59072103—
CatalystHCID 178418390HCID 178418390—
SolventEthanolHCID 702—
SolventTetrahydrofuranHCID 8028—
ProductHCID 66726181HCID 66726181100.3%

Reaction Steps

To a solution of 2-(methylsulfonyl)-5-(4-nitrophenoxy)pyridine (9.88 g) in ethanol (150 mL) and tetrahydrofuran (150 mL) was added 10% palladium carbon (1 g), and the mixture was stirred under a hydrogen atmosphere for 15 hr. Palladium carbon was removed, and the residue was concentrated under reduced pressure to give the title compound (8.9 g, yield 100%) as a pale-yellow oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08557805B2
Source datasetuspto-grants-2013_10
ORD IDord-a67f945fb6ed492fbb3ff7da7a623ae6
Source noteuspto-grants-2013_10