反应详情

A mixture of 5-(3-methyl-4-nitrophenoxy)-2-(methylsulfonyl)pyridine (12.58 g), 10% palladium carbon (2.5 g, containing water (50%)), tetrahydrofuran (200 mL), and methanol (50 mL) was stirred under a hydrogen atmosphere (balloon pressure) at room temperature for 18 hr. The catalyst was filtered off, and the obtained filtrate was concentrated under reduced pressure to give the title compound (11.4 g, yield 100%) as a pale-yellow oil.

1. filtrationThe catalyst was filtered off
2. concentrationthe obtained filtrate was concentrated under reduced pressure