Hydrogen Bromide → HCID 44218047, compound

Participants

Reaction Steps

To 0.21 g of (E)-N-(2-amino-phenyl)-3-{1-[4-(1-methyl-1H-pyrazol-4-yl)-benzenesulfonyl]-1H-pyrrol-3-yl}-acrylamide in 4 ml THF a solution of 0.169 ml of 48%-HBr (169 μL, 1.5 mmol) in 4 ml THF was added dropwise. A solid separated, which was treated with diethylether. The resulting crystalline solid was separated and dried overnight. Yield: 287 mg (100%); MP: 200° C., sinter. The compound contained 1.86 HBr/Mol.

Provenance & Evidence