HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 3-(4-Fluoro-2-propoxy-phenyl)-acrylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Propane iodide | HCID 18513226 | — |
| Reactant | 3-(4-Fluoro-2-hydroxy-phenyl)-acrylic acid methyl ester | HCID 66857693 | — |
| Product | 3-(4-Fluoro-2-propoxy-phenyl)-acrylic acid methyl ester | HCID 66855602 | 100% |
Reaction Steps
3-(4-Fluoro-2-hydroxy-phenyl)-acrylic acid methyl ester (110.5 mg) was reacted with K2CO3 (111 mg) and propane iodide (0.1 ml) at 80° C. overnight as described above to yield title compound (134 mg, 100%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08557872B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-2a69f49c048a4c0eac0cc267ae1f206f |
| Source note | uspto-grants-2013_10 |