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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1042485Generated: October 31, 2026

Butyl bromide → 2-Butoxy-4-trifluoromethyl-benzoic acid butyl ester

https://huagongshe.com/reaction/1042485

Reaction equation

Participants

RoleNameHCIDCharge
ReactantButyl bromideHCID 8002—
ReactantPotassium CarbonateHCID 11430—
Reactant2-Hydroxy-4-(trifluoromethyl)benzoic acidHCID 164578—
SolventDimethylformamideHCID 6228—
Product2-Butoxy-4-trifluoromethyl-benzoic acid butyl esterHCID 66855159—

Reaction Steps

2-Hydroxy-4-trifluoromethyl-benzoic acid (755 mg) was reacted with butylbromide (0.96 ml) and K2CO3 (1.15 g) in DMF solution as described above to yield title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08557872B2
Source datasetuspto-grants-2013_10
ORD IDord-636ee6fd91fb4f2ea2d3e00f9f50d11f
Source noteuspto-grants-2013_10