2-Butoxy-4-trifluoromethyl-benzoic acid butyl ester → 2-Butoxy-4-trifluoromethyl-benzoic acid
Reaction equation
C([O:5][C:6](=[O:22])[C:7]1[CH:12]=[CH:11][C:10]([C:13]([F:16])([F:15])[F:14])=[CH:9][C:8]=1[O:17][CH2:18][CH2:19][CH2:20][CH3:21])CCC>[Li+].[OH-]>[CH2:18]([O:17][C:8]1[CH:9]=[C:10]([C:13]([F:14])([F:15])[F:16])[CH:11]=[CH:12][C:7]=1[C:6]([OH:22])=[O:5])[CH2:19][CH2:20][CH3:21]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
2-Butoxy-4-trifluoromethyl-benzoic acid butyl ester was reacted with 1N LiOH (10 ml) as described above to yield title compound (687 mg).
Sources & evidence
- ORD record
- ord-d94e236fb9b4461c96adc444c2d5fecd
- Source dataset
- uspto-grants-2013_10
- Patent number
- US08557872B2
Reaction notes
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