HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aluminium lithium hydride → 2-Butoxy-4-trifluoromethyl-benzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Reactant | 2-butoxy-N-methoxy-N-methyl-4-trifluoromethyl-benzamide | HCID 86649967 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 2-Butoxy-4-trifluoromethyl-benzaldehyde | HCID 86649968 | 63.6% |
Reaction Steps
2-Butoxy-N-methoxy-N-methyl-4-trifluoromethyl-benzamide (825 mg) was reacted with 1 M LAH (31 ml) at −50° C. for 1 hour as described above to yield title compound (423 mg) after column chromatography (Hex/EtOAc=20/1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08557872B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-b56e6dcf665648a0af35126d9c243e98 |
| Source note | uspto-grants-2013_10 |