huagongshe.com
HRID1042488

反应详情

EQUATION

反应方程式

HRID 1042488 的结构方程式

REACTANTS

反应物

2
结构：[Al+3].[H-].[H-].[H-].[H-].[Li+]
HCID21226445

未命名化合物

结构：CCCCOc1cc(C(F)(F)F)ccc1C(=O)N(C)OC
HCID86649967

未命名化合物

PRODUCTS

生成物

1
结构：CCCCOc1cc(C(F)(F)F)ccc1C=O
HCID86649968

未命名化合物

收率 63.6%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCOC(C)=O
溶剂HCID8857

Ethyl acetate

C4H8O2

PROCEDURE

实验过程

2-Butoxy-N-methoxy-N-methyl-4-trifluoromethyl-benzamide (825 mg) was reacted with 1 M LAH (31 ml) at −50° C. for 1 hour as described above to yield title compound (423 mg) after column chromatography (Hex/EtOAc=20/1).