HuagongsheHuagongshe Chemistry Print Report · For research reference only
Butyl iodide → 3-(2-Butoxy-4-fluoro-phenyl)-acrylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Butyl iodide | HCID 10962 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-(4-Fluoro-2-hydroxy-phenyl)-acrylic acid methyl ester | HCID 66857693 | — |
| Product | 3-(2-Butoxy-4-fluoro-phenyl)-acrylic acid methyl ester | HCID 66856235 | — |
Reaction Steps
3-(4-Fluoro-2-hydroxy-phenyl)-acrylic acid methyl ester (106 mg) was reacted with K2CO3 (125 mg) and butyl iodide (0.1 ml) at 80° C. for 3 hrs as described above to yield title compound (121 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08557872B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-f462d52d93c9446bb9abba344108b4a8 |
| Source note | uspto-grants-2013_10 |