HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Iodobutane → 3-(2-Sec-butoxy-4-fluoro-phenyl)-acrylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Iodobutane | HCID 10559 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-(4-Fluoro-2-hydroxy-phenyl)-acrylic acid methyl ester | HCID 66857693 | — |
| Product | 3-(2-Sec-butoxy-4-fluoro-phenyl)-acrylic acid methyl ester | HCID 66855955 | — |
Reaction Steps
3-(4-Fluoro-2-hydroxy-phenyl)-acrylic acid methyl ester (120 mg) was reacted with K2CO3 (165 mg) and 2-iodobutan (0.12 ml) at 100° C. for 3 hrs as described above to yield title compound (105 mg)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08557872B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-62fc0347c8804a7695243e6c1ae399e8 |
| Source note | uspto-grants-2013_10 |