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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1042504Generated: November 2, 2026

2-Hydroxy-4-(trifluoromethyl)benzoic acid → HCID 58111822, compound

https://huagongshe.com/reaction/1042504

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Hydroxy-4-(trifluoromethyl)benzoic acidHCID 164578—
ReactantCyclohexylmethyl 4-methylbenzenesulfonateHCID 11807699—
ProductHCID 58111822HCID 58111822198.2%

Reaction Steps

2-Hydroxy-4-trifluoromethyl-benzoic acid (246 mg, 1.19 mmol) was reacted with toluene-4-sulfonic acid cyclohexylmethyl ester (640 mg, 2.34 mmol) as described above to give the title compound (470 mg, 99%) after purification by column chromatography.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08557872B2
Source datasetuspto-grants-2013_10
ORD IDord-a2399f00a7c0495e884d5a4d7f735aa3
Source noteuspto-grants-2013_10