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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1042733Generated: October 26, 2026

3-Amino-2-fluorobenzotrifluoride → 3-Bromo-4-chloro-N-(2-fluoro-3-(trifluoromethyl)phenyl)benzamide

https://huagongshe.com/reaction/1042733

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Amino-2-fluorobenzotrifluorideHCID 145569—
Reactant3-Bromo-4-chlorobenzoyl chlorideHCID 20229730—
Product3-Bromo-4-chloro-N-(2-fluoro-3-(trifluoromethyl)phenyl)benzamideHCID 59428039—

Reaction Steps

3-Bromo-4-chloro-N-(2-fluoro-3-(trifluoromethyl)phenyl)benzamide was synthesized from 2-fluoro-3-(trifluromethyl)aniline and 3-bromo-4-chlorobenzoyl chloride according to the procedure described in Example 183. 3-Bromo-4-chloro-N-(2-fluoro-3-(trifluoromethyl)phenyl)benzamide was obtained as a red-orange solid. MS (M−H+) 393.9; Calc'd for C14H7BrClF4NO: 395.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08557996B2
Source datasetuspto-grants-2013_10
ORD IDord-ae10da11e87e4b10a4c215a42ce4aaf4
Source noteuspto-grants-2013_10