Pyridine → tert-butyl (3RS,4RS,5SR)-4-[4-(3-benzyloxy-propoxy)-phenyl]-3-hydroxy-5-trityloxymethyl-piperidine-1-carboxylate
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][CH2:9][CH2:10][CH2:11][O:12][c:13]1[cH:14][cH:15][c:16]([CH:19]2[CH:20]([OH:34])[CH2:21][N:22]([C:27](=[O:28])[O:29][C:30]([CH3:31])([CH3:32])[CH3:33])[CH2:23][CH:24]2[CH2:25][OH:26])[cH:17][cH:18]1.[c:35]1([C:41]([Cl:42])([c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)[c:49]2[cH:50][cH:51][cH:52][cH:53][cH:54]2)[cH:36][cH:37][cH:38][cH:39][cH:40]1.[cH:55]1[cH:56][cH:57][n:58][cH:59][cH:60]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][CH2:9][CH2:10][CH2:11][O:12][c:13]1[cH:14][cH:15][c:16]([CH:19]2[CH:20]([OH:34])[CH2:21][N:22]([C:27](=[O:28])[O:29][C:30]([CH3:31])([CH3:32])[CH3:33])[CH2:23][CH:24]2[CH2:25][O:26][C:41]([c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)([c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)[c:49]2[cH:50][cH:51][cH:52][cH:53][cH:54]2)[cH:17][cH:18]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-d30d5db7280f44039dce85b362e2431c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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