Hydrochloric Acid → HCID 178526855, compound

HRID 1042954Notes

Reaction equation

HRID 1042954 reaction equation
[N+]([C:4]1[NH:5][CH:6]=[C:7]([N+:9]([O-:11])=[O:10])[N:8]=1)([O-])=O.[ClH:12]>O>[Cl:12][C:4]1[NH:5][CH:6]=[C:7]([N+:9]([O-:11])=[O:10])[N:8]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 178526857HCID 178526857, compound

Product 1

HCID 178526855HCID 178526855, compoundYield 77.1%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
95 °C

Procedure

5.0 g of 2,4-dinitroimidazole (purity 92.3%) was added to 30 mL of 35 mass % hydrochloric acid. The reaction liquid was warmed to 95° C. and the reaction was performed for 7 hours. After the reaction, 43 g of water was added and the resultant mixture was cooled to 0° C. for crystallization. The crystals were filtered and dried to obtain 3.31 g of 2-chloro-4-nitroimidazole (yield 77.1%). This was identified to be 2-chloro-4-nitroimidazole by

Workup

  1. customThe reaction liquid
  2. additionwas added
  3. filtrationThe crystals were filtered
  4. customdried

Sources & evidence

ORD record
ord-ffdb7e13bffe4470847f3080888ca766
Source dataset
uspto-grants-2013_10
Patent number
US08558005B2

Reaction notes

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