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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1043588생성일: 2026년 10월 27일

2-Methyl-2-(piperazin-1-yl)propanamide → 2-(4-((2-Chloro-4-morpholinopyrido[3,2-d]pyrimidin-6-yl)methyl)piperazin-1-yl)-2-methylpropanamide

https://huagongshe.com/reaction/1043588

반응식

참여 물질

역할이름HCID투입량
반응물2-Methyl-2-(piperazin-1-yl)propanamideHCID 21748841—
반응물4-(6-(Bromomethyl)-2-chloropyrido[3,2-D]pyrimidin-4-YL)morpholineHCID 58404978—
생성물2-(4-((2-Chloro-4-morpholinopyrido[3,2-d]pyrimidin-6-yl)methyl)piperazin-1-yl)-2-methylpropanamideHCID 58404942—

반응 단계

4-(6-(Bromomethyl)-2-chloropyrido[3,2-d]pyrimidin-4-yl)morpholine 7 (0.1 g) was reacted with 2-methyl-2-(piperazin-1-yl)propanamide via General Procedure B to give 123 mg of 2-(4-((2-chloro-4-morpholinopyrido[3,2-d]pyrimidin-6-yl)methyl)piperazin-1-yl)-2-methylpropanamide.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08563540B2
출처 데이터셋uspto-grants-2013_10
ORD IDord-ad29921853eb42e6a7d9d7874f1ca929
출처 메모uspto-grants-2013_10