1,4-Dioxane hydrochloride → (1,4-Dioxepan-6-yl)hydrazine hydrochloride

HRID 1043883Notes

Reaction equation

HRID 1043883 reaction equation
O1CCOCC1.[ClH:7].[O:8]1[CH2:14][CH:13]([N:15](C(OC(C)(C)C)=O)[NH2:16])[CH2:12][O:11][CH2:10][CH2:9]1>O1CCOCC1>[ClH:7].[O:8]1[CH2:14][CH:13]([NH:15][NH2:16])[CH2:12][O:11][CH2:10][CH2:9]1

Participants

4

Reactant 2

HCID 204431481,4-Dioxane hydrochlorideHCID 86686322t-Butyl 1-(1,4-dioxepan-6-yl)hydrazinecarboxylate

Product 1

HCID 86686315(1,4-Dioxepan-6-yl)hydrazine hydrochloride

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

A 4 M hydrogen chloride-1,4-dioxane solution (3 mL) was added to a solution of t-butyl 1-(1,4-dioxepan-6-yl)hydrazinecarboxylate (392 mg) in dioxane (3 mL). The reaction mixture was stirred at room temperature overnight and further stirred at 50° C. for 1 hour. The reaction mixture was concentrated under reduced pressure to give the title compound (341 mg).

Workup

  1. stirringfurther stirred at 50° C. for 1 hour
  2. concentrationThe reaction mixture was concentrated under reduced pressure

Sources & evidence

ORD record
ord-35794882c125414681665f7304a6bfe4
Source dataset
uspto-grants-2013_10
Patent number
US08563565B2

Reaction notes

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