1,4-Dioxane hydrochloride → (1,4-Dioxepan-6-yl)hydrazine hydrochloride

Participants

Reaction Steps

A 4 M hydrogen chloride-1,4-dioxane solution (3 mL) was added to a solution of t-butyl 1-(1,4-dioxepan-6-yl)hydrazinecarboxylate (392 mg) in dioxane (3 mL). The reaction mixture was stirred at room temperature overnight and further stirred at 50° C. for 1 hour. The reaction mixture was concentrated under reduced pressure to give the title compound (341 mg).

Provenance & Evidence