Methyl iodide → HCID 46847803, compound

HRID 1044331Notes

Reaction equation

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:18](=[O:19])[C:17]3[C:12](=[CH:13][CH:14]=[N:15][C:16]=3[NH:20][C:21]3C=CC=C[CH:22]=3)[N:11]([CH2:27]C)[CH:10]=2)=[CH:5][CH:4]=1.COC1C=CC(C2C(=O)C3C(=CC=NC=3NC3C=CC=CC=3)[NH:39][CH:38]=2)=CC=1.I[CH3:56].I[CH2:58][CH3:59]>>[CH2:1]([O:2][C:3]1[CH:4]=[CH:5][C:6]([C:9]2[C:18](=[O:19])[C:17]3[C:12](=[CH:13][CH:14]=[N:15][C:16]=3[NH:20][C:21]3[CH:22]=[N:39][CH:38]=[CH:58][CH:59]=3)[N:11]([CH3:27])[CH:10]=2)=[CH:7][CH:8]=1)[CH3:56]

Participants

Reactant 4

HCID 6328Methyl iodide

HCID 6340Iodoethane

HCID 46847433HCID 46847433, compound

HCID 46847804HCID 46847804, compound

Product 1

HCID 46847803HCID 46847803, compound

Procedure

3-(4-Methoxyphenyl)-1,4-dihydro-1-ethyl-4-oxo-5-phenylamino-1,6-naphthyridine The title compound was prepared as described in Example 2 above except that 3-(4-chlorophenyl)-1,4-dihydro-4-oxo-5-(2-phenethylamino)-1,6-naphthyridine was replaced with 3-(4-methoxyphenyl)-1,4-dihydro-4-oxo-5-phenylamino-1,6-naphthyridine and iodomethane was replaced with iodoethane. MS 372 (M+1)+.

Sources & evidence

ORD record: ord-78ef0f6ff8ea407eab2865932dcd2701
Source dataset: uspto-grants-2013_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08563579B2

Reaction notes

Loading…